ISSN 1662-4009 (online)

ey0018.9-3 | Childhood cancer and thyroid disease | ESPEYB18

9.3. Presentation and outcome of subsequent thyroid cancer among childhood cancer survivors compared to sporadic thyroid cancer: a matched national study

SC Clement , CA Lebbink , MS Klein Hesselink , JC Teepen , TP Links , CM Ronckers , HM van Santen

Eur J Endocrinol. 2020; 183: 169–180. https://pubmed.ncbi.nlm.nih.gov/32449692/This retrospective study analyzed subsequent differentiated thyroid cancer (DTC) in in a group of CCS (n=31) matched with patients affected by sporadic DTC (n=93) to compare clinical presentation and outcomes. CCS with subsequent DTC were identified by two source populations: the DCOG-LATER cohort o...

ey0017.9-2 | Fertility-Related Issues | ESPEYB17

9.2. Pregnancy, time to pregnancy and obstetric outcomes among female childhood cancer survivors: Results of the DCOG LATER-VEVO study

Dijk M Van , FE van Leeuwen , A Overbeek , CB Lambalk , MM van den Heuvel-Eibrink , W van Dorp , WJ Tissing , LC Kremer , JJ Loonen , B Versluys , D Bresters , CM Ronckers , HJ van der Pal , CCM Beerendonk , GJL Kaspers , E van Dulmen-den Broeder , MH van den Berg

To read the full abstract: J Cancer Res Clin Oncol. 2020 Jun;146(6):1451–1462. marloes.vandijk@amsterdamumc.nlChemo- and radiotherapy administered during childhood may compromise female reproductive function leading to premature depletion of the ovarian follicle pool. Childhood cancer survivors (CCS) women who pursue pregnancy may experience a lengthening of the time required to become pr...

ey0016.9-8 | Fertility Issues in Chronic Diseases: New Insights | ESPEYB16

9.8. Long-term effects of childhood cancer treatment on hormonal and ultrasound markers of ovarian reserve

MH van den Berg , A Overbeek , CB Lambalk , GJL Kaspers , D Bresters , MM van den Heuvel-Eibrink , LC Kremer , JJ Loonen , HJ van der Pal , CM Ronckers , WJE Tissing , AB Versluys , M van der Heiden-van der Loo , AC Heijboer , M Hauptmann , JWR Twisk , JSE Laven , CCM Beerendonk , FE van Leeuwen , E van Dulmen-den Broeder , DCOG LATER-VEVO Study Group

Hum Reprod. 2018 Jul 6. [Epub ahead of print]. doi: 10.1093/humrep/dey229Childhood cancer treatment may compromise ovarian function in female childhood cancer survivors (CCSs), leading to delayed or arrested puberty, infertility, subfertility and adverse pregnancy outcomes. This Dutch nationwide retrospective cohort study collected measurements performed between 2008 and 2...

ey0020.7-8 | Bone Health in Childhood Cancer Survivors | ESPEYB20

7.8. Risk and determinants of low and very low bone mineral density and fractures in a national cohort of Dutch adult childhood cancer survivors (DCCSS-LATER): a cross-sectional study

JE van Atteveld , DTC de Winter , VG Pluimakers , M Fiocco , RAJ Nievelstein , MGG Hobbelink , ACH de Vries , JJ Loonen , E van Dulmen-den Broeder , HJ van der Pal , SMF Pluijm , LCM Kremer , CM Ronckers , M van der Heiden-van der Loo , AB Versluijs , M Louwerens , D Bresters , HM van Santen , DS Olsson , I Hoefer , SAA van den Berg , J den Hartogh , WJE Tissing , SJCMM Neggers , MM van den Heuvel-Eibrink , Dutch LATER study group

Brief summary: This Dutch cross-sectional study aimed to assess risk factors for impaired bone mineral density (BMD) and fractures (particularly vertebral fractures) in adult survivors of childhood cancer. The relationships between low BMD (Z-score ≤–1), very low BMD (Z-score ≤–2), fractures, vertebral fractures, and demographic, treatment-related, endocrine, and lifestyle-related factors was analyzed by logistic regression.<p class=...